PanCAN Scientific Summit 2025

8:50 — 9:10 

Immunopeptidomics to Accelerate Immunotherapies in Pancreas Cancer

William Freed-Pastor, MD, PhD, Dana-Farber Cancer Institute
Grant funded in memory of Llewellyn Bixby IV, through a gift made by his family

9:10 — 9:30 

The Time Toxicity of Cancer Care

Arjun Gupta, MD, University of Minnesota Medical School
Grant funded by an anonymous donor

9:30 — 9:50 

Mechanisms of Cancer-Nerve Dynamics in Pancreatic Cancer

William Hwang, MD, PhD, Massachusetts General Hospital
Funded by Rick Star in Memory of Janet Ranta Star

9:50 — 10:10 

The Role of Stromal Cadherin 11 in Chemotherapy Response in Pancreatic Cancer

Ivana Peran, PhD, Georgetown University

10:25 — 10:45

Chemotherapy Sensitivity Biomarkers for Pancreatic Ductal Adenocarcinoma Through Master Regulator Analysis

Basil Bakir, MD, PhD, Columbia University (during grant term)

10:45 — 11:05 

Glycine availability in the PDAC tumor microenvironment as a driver of chemoresistance

Guillaume Cognet, PhD, University of Chicago
Grant funded by the Francois Wallace Monahan Fund in loving memory of Michael Insel

11:05 — 11:25 

Understanding mechanisms of response and resistance to RAS-pathway inhibition in pancreatic cancer

Andrew Aguirre, MD, PhD (on behalf of Julien Dilly, MS), Dana-Farber Cancer Institute
Grant funded by the Francois Wallace Monahan Fund in loving memory of Michael Insel

11:25 — 11:45 

Pelareorep-based immunotherapy for the treatment of metastatic PDAC

Thomas Heineman, MD, PhD, Oncolytics Biotech, Inc.
Grant funded in memory of Skip Viragh

11:45 — 12:05 

RAMP 205 Clinical Trial in Front-Line Metastatic Pancreatic Cancer

John Hayslip, MD, Verastem Oncology
Grant supported by 1440 Foundation, the Gail V. Coleman-Kenneth M. Bruntel Research Fund, Lyda Hill Philanthropies, The Bern Schwartz Family Foundation, Cynthia Stroum, and in memory of Skip Viragh

12:05 — 12:25 

RAMP 205 Translational Analysis

Jonathan Pachter, PhD, Verastem Oncology

Precision Promise: The End Is Just the Beginning

Cassadie Moravek, Senior Director, Precision Promise Portfolio and Program Management, PanCAN

IMPACT PDAC — Innovative Master Protocol to Accelerate Clinical Therapeutics for Pancreatic Ductal Adenocarcinoma

Heather Kling, PhD, Global Coalition for Adaptive Research

Precision Promise Research to Drive Future Progress

Kristina Harris, PhD, Senior Director, Translational Research & Grants, PanCAN

1:55 — 2:05 

SPARK: PanCAN’s Platform for Collaborative Access and Analysis of Patient Health Data

Kawther Abdilleh, PhD, Director, Data Science and Informatics, PanCAN

2:05 — 2:25 

Mutant Kras alleles drive distinct immunological phenotypes in pancreatic cancer

Despina Siolas, MD, PhD, Weill Cornell Medicine

2:25 — 2:45 

Nationwide telemedicine clinical trial for FGFR-altered pancreatic cancer

Sameek Roychowdhury, MD, PhD, Ohio State University